Table 2.

Some important drugs currently in clinical trials.

Name of the Drug	Company	Mechanism of Action	Clinical Trial	Symptoms to be Relieved
Brexpiprazole	Otsuka &Lundbeck	D2 partial agonist	Phase III	agitation
Tetrahydrocannabinol	Johns Hopkins University	CB1/CB2 partial agonist	Phase II trials
Nabilone	Sunnybrook Health Sciences Centre	semisynthetic cannabinoid derivative	small-scale phase III
Pimavanserin	Acadia	selective 5-HT2A serotonin inverse agonist	phase II/III	psychotic
Suvorexant	Merck	dual antagonists of the orexin receptors	Phase III	insomnia
Lemborexant	Eisai	dual antagonists of the orexin receptors	Phase II