Table 1.

Characteristics of study cohorts in included databases.

	HEALTHVERITY	Hospital CDM	Open Claims	OPTUM EHR	OPTUM SES	Premier	VA-OMOP
N	22,887	77,853	533,997	36,717	4,336	156,187	10,951
Age
Age < 65 (n [%])	9,954 (43.5%)	44,753 (57.5%)	256,270 (48.0%)	22,014 (60.0%)	1,531 (35.3%)	81,208 (52.0%)	3,836 (35.0%)
Age >= 65 (n [%])	12,933 (56.5%)	33,100 (42.5%)	277,727 (52.0%)	14,703 (40.0%)	2,805 (64.7%)	74,979 (48.0%)	7,115 (65.0%)
Sex
Male (n [%])	11,769 (51.4%)	39,911 (51.3%)	268,957 (50.4%)	18,495 (50.4%)	2,354 (54.3%)	81,155 (52.0%)	10,225 (93.4%)
Female (n [%])	11,118 (48.6%)	37,869 (48.6%)	264,987 (49.6%)	18,222 (49.6%)	1,982 (45.7%)	75,032 (48.0%)	726 (6.6%)
Comorbidities
Asthma (n [%])	1,004 (4.4%)	5,149 (6.6%)	82,087 (15.4%)	4,922 (13.4%)	628 (14.5%)	10,497 (6.7%)	1,153 (10.5%)
Autoimmune condition (n [%])	1,215 (5.3%)	5,793 (7.4%)	136,735 (25.6%)	4,352 (11.9%)	931 (21.5%)	6,387 (4.1%)	3,156 (28.8%)
Chronic kidney disease (n [%])	2,622 (11.5%)	12,016 (15.4%)	164,710 (30.8%)	8,350 (22.7%)	1,357 (31.3%)	24,282 (15.5%)	3,958 (36.1%)
COPD (n [%])	2,213 (9.7%)	10,153 (13.0%)	118,421 (22.2%)	6,777 (18.5%)	1,066 (24.6%)	13,699 (8.8%)	4,641 (42.4%)
Diabetes (n [%])	3,880 (17.0%)	22,470 (28.9%)	254,505 (47.7%)	12,227 (33.3%)	1,844 (42.5%)	45,790 (29.3%)	5,839 (53.3%)
Heart disease (n [%])	5,178 (22.6%)	22,423 (28.8%)	319,842 (59.9%)	17,185 (46.8%)	2,634 (60.7%)	47,198 (30.2%)	7,421 (67.8%)
Hypertension (n [%])	6,410 (28.0%)	36,071 (46.3%)	390,171 (73.1%)	21,290 (58.0%)	2,977 (68.7%)	74,311 (47.6%)	9,087 (83.0%)
Obesity (n [%])	2,238 (9.8%)	14,878 (19.1%)	191,071 (35.8%)	20,188 (55.0%)	1,626 (37.5%)	35,462 (22.7%)	5,677 (51.8%)