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. 2020 Dec 2;15:339. doi: 10.1186/s13023-020-01617-z

Table 1 .

Urine creatine panel metabolites and their age and sex related distribution

Urine creatine panel metabolites Age dependent reference range Numbers Female Male Statistical analysis (non-parametric Kruskal–Wallis rank sum test)
Number Number
Mean ± SD Mean ± SD
Range Range
Urine guanidinoacetate 0–60 months (Reference range 5–150 mmol/mol creatinine) Number 58 109 p = 0.001856*
Average ± SD 104.0 ± 51.9 81.81 ± 44.3
Median 100 71
Range 15.0–250.0 9.00–281.00
2.5th percentile 25 26
25th percentile 61 54.25
75th percentile 138.5 93.75
97.5th percentile 204.9 195.5
60–192 months (reference range 15–130 mmol/mol creatinine) Number 48 67 p = 0.569
Average ± SD 64.25 ± 39.6 69.21 ± 87.8
Median 54 54
Range 8–171 1–573
2.5th percentile 10.275 10.625
25th percentile 37 34.25
75th percentile 85.7 78.5
97.5th percentile 151.625 237.025
192–228 months (reference range 11–60 mmol/mol creatinine) Number 6 9 p = 0.07825
Average ± SD 60.86 ± 29.1 34.90 ± 15.8
Median 44 34
Range 29–97 13–65
2.5th percentile 30.35 13.9
25th percentile 39.5 24.5
75th percentile 88.5 42.75
97.5th percentile 96.4 61.4
Urine creatine 0–60 months (reference range 14–830 mmol/mol creatinine) Number 58 109 p = 0.03946*
Average ± SD 777.3 ± 490.0 645.6 ± 537.0
Median 720 533.5
Range 14.0–2333.0 4.0–3915.0
2.5th percentile 31.85 13.925
25th percentile 383 327.5
75th percentile 1059 885.2
97.5th percentile 1710.75 1844.43
60–192 months (reference range 16–649 mmol/mol creatinine) Number 48 67 p = 0.8339
Average ± SD 424.83 ± 1217.0 290.8 ± 471.0
Median 153 161
Range 3.00–8756.00 3.0–3518.0
2.5th percentile 5.825 4
25th percentile 25.25 28
75th percentile 398.25 389
97.5th percentile 1080.78 907.075
192–228 months Number 6 9 p = 0.6594
(reference range 19–173 mmol/mol creatinine) Average ± SD 47.0 ± 64.6 68.6 ± 164.0
Median 17 11
Range 5.0–186.0 5.0–531.0
2.5th percentile 5.4 5.225
25th percentile 9 8
75th percentile 51.5 16.5
97.5th percentile 167.1 428.625

Urine creatine panel metabolites and their age and sex related distribution in 297 patients who underwent urine creatine panel measurement for the diagnostic investigations are listed