Table 1.
Frequency distribution of pfdhfr and pfdhps point mutations for P. falciparum isolates from Jazan, Saudi Arabia (n = 151)
| Markera | Number | % |
|---|---|---|
| Pfdhfr | ||
| A16V | ||
| Wild | 151 | 100 |
| Mutated | 0 | 0 |
| C50R | ||
| Wild | 151 | 100 |
| Mutated | 0 | 0 |
| N51I | ||
| Wild | 23 | 15.2 |
| Mutated | 128 | 84.8 |
| C59R | ||
| Wild | 94 | 62.3 |
| Mutated | 57 | 37.7 |
| S108N | ||
| Wild | 23 | 15.2 |
| Mutated | 128 | 84.8 |
| I164L | ||
| Wild | 151 | 100 |
| Mutated | 0 | 0 |
| Pfdhps | ||
| S436A/F | ||
| Wild | 151 | 100 |
| Mutated | 0 | 0 |
| A437G | ||
| Wild | 66 | 43.7 |
| Mutated | 85 | 56.3 |
| K540E | ||
| Wild | 73 | 48.3 |
| Mutated | 78 | 51.7 |
| A581G | ||
| Wild | 151 | 100 |
| Mutated | 0 | 0 |
| A613T/S | ||
| Wild | 151 | 100 |
| Mutated | 0 | 0 |
| I640F | ||
| Wild | 151 | 100 |
| Mutated | 0 | 0 |
aMutant alleles are bold and underlined