Table 4.

Case 1 p-value rankings for HDR2 Animal compared to Control 1 Animal

					Degree of Experimental Methylation Level Higher Than Control
Chromosome	CpG Island Start Location	CpG Island End Location	p-value	CpG Count	1–20% Proportion	1–20%	21–40%	41–60%	61–80%	81–100%
6	113,076,186	113,077,861	5.384E-23	135	0.229	19	45	19	0	0
16	4,846,725	4,846,950	2.937E-10	12	0.000	0	1	10	1	0
1	126,092,971	126,093,200	3.224E-10	16	0.313	5	11	0	0	0
12	84,038,314	84,038,998	3.593E-10	37	0.406	13	14	5	0	0
6	3,200,773	3,201,615	8.468E-10	35	0.355	11	20	0	0	0
7	31,208,206	31,208,620	1.111E-08	24	0.455	10	11	1	0	0
3	101,982,373	101,982,595	4.617E-08	27	0.480	12	9	4	0	0
10	126,861,656	126,861,911	1.620E-07	15	0.200	3	7	5	0	0
2	34,639,014	34,639,339	2.409E-07	22	0.400	8	10	2	0	0

The p-value represents the upper-tail p-value for the hypothesis test of higher methylation in the experimental mouse than the control mouse. The CG count includes the total number of CGs in the CpG island. The proportion and category counts only refer to the number of CGs where the experimental CG methylation level is higher than the control CG methylation level