Table 6.

Case 1 p-value rankings for Control 2 Animal compared to Control 1 Animal

					Degree of Experimental Methylation Level Higher Than Control
Chromosome	CpG Island Start Location	CpG Island End Location	p-value	CpG Count	1–20% Proportion	1–20%	21–40%	41–60%	61–80%	81–100%
11	6,006,144	6,007,748	4.011E-20	27	0.000	0	1	4	14	8
4	134,159,558	134,164,691	5.662E-13	28	0.179	5	14	7	2	0
8	85,129,693	85,132,058	2.147E-09	10	0.000	0	7	3	0	0
8	10,978,436	10,978,759	2.607E-09	12	0.167	2	10	0	0	0
15	93,908,948	93,909,153	8.615E-08	10	0.000	0	9	1	0	0
4	146,941,454	146,942,785	2.027E-07	79	0.321	18	25	13	0	0
5	147,029,103	147,029,460	2.538E-07	15	0.467	7	7	1	0	0
15	38,118,394	38,118,655	3.010E-07	10	0.000	0	9	1	0	0
5	129,918,271	129,918,590	3.579E-07	14	0.286	4	5	5	0	0
3	69,393,711	69,394,087	5.160E-07	13	0.231	3	10	0	0	0

The p-value represents the upper-tail p-value for the hypothesis test of higher methylation in the experimental mouse than the control mouse. The CG count includes the total number of CGs in the CpG island. The proportion and category counts only refer to the number of CGs where the experimental CG methylation level is higher than the control CG methylation level