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. 2020 Dec 2;20:1180. doi: 10.1186/s12885-020-07660-0

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Overexpression of ectopic LAD1 promotes migration and invasion of SW480 cells in vitro. a LAD1 expression increased in SW480 cells transfected with ectopic LAD1 (LAD1) compared with counterpart cells with mock vector (CTL). b and c LAD1 overexpression increased the migration and invasion of SW480 cells determined by Transwell assays. Representative images of migrated and invaded cells are shown in (b). Relative cell numbers of migrated and invaded cells per well were normalized by the numbers of CTL cells with those of LAD1 cells (c). Error bars represent the mean standard deviation (n = 3; *, p < 0.05)