Table 1.
Details of selective decontamination for included RCTs
| No. of patients | |||||||
|---|---|---|---|---|---|---|---|
| Reference | Year | Control | SDD | Resection | Perioperative parenteral antibiotics | SDD | Regimen |
| Schardey et al.16 | 1997 | 103 | 102 | Gastrectomy | Cefotaxime | Polymyxin B 100 mg, tobramycin 80 mg, amphotericin B 500 mg, vancomycin 125 mg | 4 times daily, from 1 day before surgery to POD7 |
| Riedl et al.20 | 2001 | 16 | 12 | Transthoracic resection of oesophagus and cardia | Cefazolin | Polymyxin B 100 mg, tobramycin 80 mg, amphotericin B 200 mg | 4 times daily, from 4–7 days before surgery to POD7 |
| Farran et al. 17 | 2008 | 51 | 40 | Gastrectomy, oesophagectomy | Amoxycillin/clavulanic acid | Erythromycin 500 mg, gentamicin 80 mg, nystatin sulphate 100 mg | 4 times daily, from 12 h before surgery to POD5 |
| Roos et al. 11 | 2011 | 43 | 48 | Oesophageal, gastric and hepatopancreatobiliary resections | Cefuroxime/metronidazole | Polymyxin B 100 mg, tobramycin 80 mg, amphotericin B 500 mg | 4 times daily, from 2 days before surgery until normal bowel function or minimum of POD3 |
SDD, selective decontamination of the digestive tract; POD, postoperative day.