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. 2020 Dec 1;20:189. doi: 10.1186/s12894-020-00760-w

Table 2.

Comparison of COL1A1 and COL6A1 expressions based on hypospadias type and penile curvature severity

 Hypospadias type Distal Hypospadias Proximal Hypospadias Control P-value
COL1A1 0.88 (0.38–2.53) 0.76 (0.33–2.57) 1.85 (0.24–4.61) 0.024*
COL6A1 0.54 (0.16–4.35) 0.57 (0.18–1.38) 0.93 (0.17–4.06) 0.018*
Penile curvature Severity Mild (n = 14) Moderate (n = 12) Severe (n = 14) P-value
COL1A1 1.56 (0.47–2.57) 0.69 (0.33–1.59) 0.73 (0.38–1.11) 0.003*
COL6A1 0.90 (0.16–4.35) 0.57 (0.23–1.04) 0.44 (0.18–0.89) 0.037*

*, significant result p < 0.05 (Kruskal Wallis test)