Table 2.
Comparison of COL1A1 and COL6A1 expressions based on hypospadias type and penile curvature severity
Hypospadias type | Distal Hypospadias | Proximal Hypospadias | Control | P-value |
---|---|---|---|---|
COL1A1 | 0.88 (0.38–2.53) | 0.76 (0.33–2.57) | 1.85 (0.24–4.61) | 0.024* |
COL6A1 | 0.54 (0.16–4.35) | 0.57 (0.18–1.38) | 0.93 (0.17–4.06) | 0.018* |
Penile curvature Severity | Mild (n = 14) | Moderate (n = 12) | Severe (n = 14) | P-value |
COL1A1 | 1.56 (0.47–2.57) | 0.69 (0.33–1.59) | 0.73 (0.38–1.11) | 0.003* |
COL6A1 | 0.90 (0.16–4.35) | 0.57 (0.23–1.04) | 0.44 (0.18–0.89) | 0.037* |
*, significant result p < 0.05 (Kruskal Wallis test)