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. 2020 Nov 17;21(1):48. doi: 10.3892/ol.2020.12309

Figure 2.

Figure 2.

Analysis of the expression levels of MTL5 mRNA isolated by laser microdissection revealed (A) a significantly higher level of MTL5 mRNA expression in NSCLC cancer cells compared with the control, while (B) no significant differences were found in particular NSCLC subtypes. The statistical analysis of the immunohistochemistry expression of tesmin revealed that both (C) cytoplasmic and (D) nuclear expression levels were significantly higher in NSCLC cells compared with the control. (E) Cytoplasmic tesmin expression was higher in adenocarcinoma, while (F) nuclear expression was higher in squamous cell carcinoma (Mann-Whitney test; *P<0.05; **P<0.01; ****P<0.0001). MTL5, tesmin; NSCLC, non-small cell lung cancer; RQ, relative quantification; IRS, immunoreactive score΄ NSCLC, Non-small cell lung cancer.