Table V.
Univariate Cox analysis of overall survival of patients with squamous cell carcinoma of the lung.
| Univariate Cox analysis of survival | ||||
|---|---|---|---|---|
| Characteristics | P-value | Hazard ratio | 95% CI lower | 95% CI upper |
| TTF-1 (negative vs. positive) | 0.7255 | 0.8774 | 0.4227 | 1.8213 |
| Clinical stage (I–II vs. III–IV) | 0.0614 | 1.6079 | 0.9775 | 2.6447 |
| pT (pT1-2 vs. pT3-4) | 0.0206 | 1.9206 | 1.1052 | 3.3377 |
| pN (pN0 vs. pN1-3) | 0.4125 | 1.3751 | 0.6420 | 2.9452 |
| Necrosis, % (continuous) | 0.6559 | 0.9575 | 0.7908 | 1.1592 |
| Histological grade (G1 vs. G2-3) | 0.3497 | 0.5671 | 0.1727 | 1.8619 |
| Tesmin IRS (0 vs. 1–12) | 0.4507 | 1.7353 | 0.4143 | 7.2686 |
| Tesmin nuclear (0 vs. 1–4) | 0.5495 | 1.8384 | 0.2503 | 13.5045 |
| MCM-5 (0–2 vs. 3–4) | 0.9938 | 0.9920 | 0.1321 | 7.4486 |
| MCM-7 (0–3 vs. 4) | 0.3132 | 0.8703 | 0.5433 | 1.4610 |
| Ki-67 (0–2 vs. 3–4) | 0.4511 | 0.7507 | 0.3562 | 1.5824 |
IRS, immunoreactive score; MCM, minichromosome maintenance protein; TTF-1, thyroid transcription factor 1.