Table I.

Clinical trials of innate immune cells based immunotherapy that have been registered in patients with HCC.

Type of innate immune cells	Phase of clinical trial	Type of vaccine	Recruitment status	Clinicaltrials.gov identifier
DCs	Phase I	ADCC and TACE	Recruiting	NCT03086564
DCs	Phase I	DCs vaccine and microwave ablation	Recruiting	NCT03674073
DCs	Phase II	DCs vaccine and cyclophosphamide, and radical surgery/TACE/targeted agents	Not yet recruiting	NCT04317248
NK cells	Phase I/II	Allogeneic NK cells and targeted drug	Recruiting	NCT04162158
NK cells	Phase II	Allogeneic NK cells after TACE	Completed	NCT02854839
NK cells	Phase I	Allogeneic NK cell or/and immune checkpoint inhibitors	Recruiting	NCT03841110

ADCC, activated dendritic cells combined with cyclophosphamide; TACE, transcatheter arterial chemoembolization; DCs, dendritic cells; NK cells, natural killer cells.