Table 7.
Maxillary sinus lift using different bone grafts in oral and maxillofacial surgery.
| Ref. | Type of Study | Type of Graft | Method of Evaluation—In Vitro/In Vivo | Sample Size | Conclusions |
|---|---|---|---|---|---|
| [193] | Randomized clinical trial (NCT03496688) | MCBA FDBA ABB EB HA-TCP-30/70 BC |
Histological and histomorphometric analysis | 6 patients | All materials showed good biocompatibility and Osseo conductivity with FDBA as the best material, but only one patient per sample was used, so a larger sample size is required. |
| [194] | Randomized split-mouth study (NCT03682315) | ACB + ABB ACB + BP |
Radiographic analysis, mRNA analysis, histopathological analysis, Immunohistochemistry, TEM | 8 patients | Biphasic psychogenic biomaterial (BP) induced a higher radiographical vertical resorption and graft collapse in comparison with the combination with an organic bovine bone (ABB). |
| [195] | Randomized clinical trial | DPBM vs. DBBM | CT and trephine biopsy histology | 11 participants for PPA, 12 ITT |
Porcine bone (DPBM) showed comparable results with the widely used bovine bone (DBBM). A larger sample size and more extended studies are still required. |
| [196] | Randomized clinical trial | MBS BBS |
Histological Histomorphometric CBCT |
60 patients | BBS remains more stable in terms of volume maintenance and radiological graft homogeneity after a healing period of 6 months. |
| [197] | Randomized clinical trial | Calcium phosphate crystal double- coated bovine bone and an organic bovine bone |
Histological Histomorphometric radiographic |
33 patients | Both materials showed comparable histomorphometric and radiographic results. |
| [198] | Randomized split-mouth study (NCT03077867) | NHA ABB |
Histomorphometric | 28 patients | After six months of healing, no statistically significant difference was present in histomorphometric outcomes between the NHA and ABB groups. |
Mineralised solvent-dehydrated bone allograft (MCBA), freeze-dried mineralised bone allograft (FDBA), anorganic bovine bone (ABB), equine-derived bone (EB), synthetic micro-macroporous biphasic calcium-phosphate block consisting of 70% beta-tricalcium phosphate and 30% hydroxyapatite (HA-TCP 30/70), or bioapatite-collagen (BC); Bio-Oss®Spongiosa (Autogenous cortical bone (ACB) + Autogenous Bovine Bone (ABB)) Symbios® Biphasic BGM (ACB + Biphasic psychogenic(BP)); Transmission Electron microscopy (TEM); Deproteinized porcine bone mineral (DPBM), demineralised bovine bone mineral (DBBM), Per-protocol analysis (PPA), Intention to treat analysis (ITT); monophasic bone substitute (100% ß-TCP) (MBS); a biphasic bone substitute (60% HA and 40% ß-TCP) (BBS); Pure sintered nanohydroxyapatite (NHA); and anorganic bovine bone (ABB).