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. 2020 Oct 14;5(4):53. doi: 10.3390/biomimetics5040053

Table 2.

Parameters used for chlorin-based photosensitizers immobilized on carbon dots as photosensitizers against cancer.

Entry Carbon Material Concentration Irradiation Incubation Time Cancer Cell Lines Results Ref
1 Chlorin e6–conjugated C-dots 0–50 µM 30 mW/cm2 (3 min) 24 h MGC803 cells ~10% (cell viability) [101]
2 Chlorin e6–carbon dot 1 µM 100 mW/cm2 (10 min) 4 h B16F10 cells ~10% (cell viability) [102]
3 Chlorin e6–polyethyleneimine-coated carbon nanodots 2.6 μg/mL 15.5 mW/cm2 (60 min) 24 h HeLa cancer cells 20% (cell viability) [103]
4 Layered double hydroxides–chlorin e6–carbon dots 0–10 μg/mL 27 J/cm2 24 h HeLa cancer cells 9.8% (cell viability) [104]
5 Chlorin e6–carbon dot 3.0 mg/kg body weight (b.w.) 0.5 W/cm2 (10 min) 24 h BALB/c athymic nude mice (A549 cells) Volume tumor was decreased (up to 80%) [105]