TABLE 2.
CVD risk factors in adolescents and young adults with T1D and T2D
| Variable | Mean ± SD | |
|---|---|---|
| T1D (N = 1376) | T2D (N = 157) | |
| LDL-C (mg/dL) | 93.1 ± 22.0 | 99.4 ± 29.8 |
| WHtR | 0.46 ± 0.05 | 0.60 ± 0.09 |
| MAP (mmHg) | 78.2 ± 7.6 | 87.1 ± 7.3 |
| HbA1c (%) | 8.4 ± 1.3 | 8.3 ± 2.3 |
| HbAa1c (mmol/mol) | 67.9 ± 14.4 | 67.6 ± 25.4 |
| ACR (median [Q1, Q3]) | 7.7 (5.3, 13.4) | 8.9 (5.2, 23.7) |
| ACR ≥ 30 (count [%]) | 140 (10.4) | 35 (22.9) |
| IS score | 8.8 ± 2.6 | 4.1 ± 1.6 |
| PWV (m/s)a | 5.5 ± 1.0 | 6.9 ± 1.4 |
| Elevated ASb (count [%]) | 116 (8.4) | 77 (49.0) |
Note: Table entries are mean ± SD unless otherwise indicated. Data are the mean of baseline and follow-up values except the PWV which was only measured at the follow up visit.
Abbreviations: T1D, type 1 diabetes; T2D, type 2 diabetes; LDL-C, LDL-cholesterol; WHtR, waist to height ratio; MAP, mean arterial pressure; ACR, albumin to creatinine ratio; IS score, insulin sensitivity score; PWV, pulse wave velocity.
a
One high outlier winsorized to the next highest value in the analysis dataset.
b
Cut point based on 90th percentile from CVD control group (6.8 m/s for PWV).