Table II.
Patient characteristics on day 0 (D0): demographics, comorbidities, laboratory parameters, and history
| Total (N = 72) | DVT-free (n = 65) | DVT (n = 7) | P value | |
|---|---|---|---|---|
| Age | 66.3 (±11.9) | 65.9 (±12.4) | 69.3 (±6.80) | .55 |
| Sex | ||||
| Female | 28 (39) | 27 (41.5) | 1 (14.3) | .091 |
| Male | 44 (61) | 38 (58.5) | 6 (85.7) | |
| D-dimer <500 ng/mL | 2289 (±4312) N = 64 | 1622 (±2408) N = 58 | 9652 (±10,205) N = 6 | <.01 |
| CRP 0-3 mg/L | 181 (±76.3) | 96.1 (±75.0) | 67.6 (±58.4) | .37 |
| BMI (kg/m2) | 28.9 (±11.2) n = 63 | 27.7 (±5.04) n = 56 | 28.1 (±2.65) n = 7 | .94 |
| GFR >90 mL/min | 80.5 (±28.5) | 78.6 (±28.2) | 95.7 (±30.2) | .26 |
| Symptoms onset to D0 | 10.6 (±5.49) | 10.2 (±5.49) | 13.1 (±5.52) | .095 |
| Hypertension | 35 (53.8) | 31 (47.7) | 4 (57) | .71 |
| Diabetes | 13 (20) | 11 (17) | 2 (28.6) | 1 |
| Smoking | 8 (11) | 7 (10.8) | 1 (14.3) | .18 |
| Hypercholesterolemia | 24 (33.3) | 23 (35.4) | 1 (14.3) | .42 |
| Lymphopenia (<1.2 × 10.9/L) | 55 (76.4) | 51 (78.5) | 4 (57) | 1 |
| Sleep apnea syndrome | 5 (7) | 2 (3) | 3 (42.8) | .01 |
| Pulmonary embolism | 3 (4.16) | 1 (1.53) | 2 (28.6) | <.01 |
| Proximal DVT | 3 (4.2) | 0 (0) | 3 (43) | – |
| Distal DVT | 4 (5.5) | 0 (0) | 4 (57) | – |
| Signs and symptoms of DVT | – | – | 2 (28.6) | – |
| No signs and symptoms of DVT | – | – | 5 (71.5) | – |
| Medical history of VTE | 2 (2.8) | 1 (1.5) | 1 (14.3 | – |
| Atrial fibrillation | 2 (2.8) | 1 (1.5) | 1 (14.3) | – |
| Medical history of PAD | 5 (7) | 4 (6) | 1 (14.3) | – |
| Medical history of coronary diseases | 11 (15.3) | 10 (15.4) | 1 (14.3) | – |
| Antiplatelets | 12 (16.7) | 10 (15.4) | 2 (28.6) | – |
| DOACs | 4 (5.6) | 3 (5.6) | 1 (14.3) | – |
| Vit K antagonist | 1 (1.4) | 1 (1.5) | 0 (0) | – |
| Active cancer | 0 (0) | 0 (0) | 0 (0) | – |
| History of cancer | 3 (4.2) | 3 (4.6) | 0 (0) | – |
| COPD | 2 (2.8) | 1 (1.5) | 1 (14.3) | – |
| Leg ulcer | 1 (1.4) | 1 (1.5) | 0 (0) | – |
| Medical history of thrombophilia | 2 (2.8) | 1 (1.5) | 1 (14.3) | – |
| Medical history of immunologic diseases | 1 (1.4) | 0 (0) | 0 (0) | – |
| Venous insufficiency | 5 (7) | 4 (6.15) | 1 (14.3) | – |
| MARF | 7 (9.7) | 7 (10.8) | 0 (0) | – |
| Treatment (Sartans) | 5 (7) | 4 (6) | 1 (14.3) | – |
| Chronic renal failure | 4 (5.6) | 4 (6) | 0 (0) | – |
BMI, Body mass index; COPD, chronic obstructive pulmonary diseases; CRP, C-reactive protein; D0, day 0; DOAC, direct oral anticoagulant; DVT, deep venous thrombosis; GFR, glomerular filtration rate; IQR, interquartile range; M, median; MARF, moderate acute renal failure; PAD, peripheral arterial disease; Vit, vitamin; VTE, venous thromboembolism.
Continuous data are expressed as the mean ± standard deviation, and categorical data are expressed as number (%).