Overview of CNN architecture with 7 layers to classify different pathologic response groups: pCR vs. non-pCR, and GR vs. non-GR. Six sets of images are used as inputs: one T2, two DWI with b=0 and 800 s/mm2, and three DCE images (L1, L2 and L3). The analysis is done using pre-treatment MR alone and mid-RT alone (6 input channels), and patients with both pre-treatment and mid-RT together (12 input channels).