Table 1.
Shared miR-145 targets in human embryonic stem cells and cancer stem cells.
| Target genes | 3’UTR target site location | Types of cancer | References |
|---|---|---|---|
| OCT4 (POU5F1) | 138–157; 1276–1297 | LSCC, cervical, NSCLC | (37, 38, 42, 43, 48) |
| SOX2 | 1–20; 1391–1411 | Colorectal, LSCC, cervical | (32, 37, 38, 42, 43) |
| KLF4 | 256–285 | LSCC | (37, 42) |
| NANOG | 764–790 | Cervical | (38, 43) |
| c-MYC (MYC) | Unknown | Prostate, breast, colon, NSCLC | (44, 46, 47) |
LSCC, laryngeal squamous cell carcinoma; NSCLC, non-small cell lung cancer.
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