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. Author manuscript; available in PMC: 2021 Oct 15.
Published in final edited form as: Cell Chem Biol. 2020 Aug 13;27(10):1241–1249.e4. doi: 10.1016/j.chembiol.2020.07.021

Table 2.

Single-round transcription termination efficiencies for ligands to the ZTP riboswitch

Compound T50, μM
1 37 ± 12
3 N.D.a
4 N.D.
7 5.7 ± 0.9
8 16 ± 3
12 4.8 ± 0.9
13 5.8 ± 1.5
a

Not determined (N.D.) as no activity was observed.

Values are the mean ± standard deviation, with n = 3 independent experiments for all compounds.