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. 2020 Dec 2;15(12):e0234588. doi: 10.1371/journal.pone.0234588

Table 3. Characteristics for patients developing TB during and after IPT in Kenya, 2015–2018.

Category Overall n (%) TB Diagnosis P-value
During IPT n (%) Post IPT n (%)
Age group (yrs)
    0–9 4 (9.5) 1(6.2) 3 (11.5) 0.5
    10–14 1 (2.3) 0 (0) 1 (3.8)
    15–19 3 (7.1) 2 (12.5) 1 (3.8)
    20–25 2 (4.7) 0 (0) 2 (7.6)
    25+ 32 (76.1) 13 (81.2) 19 (73.0)
Sex
    Female 24 (57.1) 5 (31.2) 19 (73) 0.008
    Male 18 (42.8) 11(68.7) 7 (26.9)
Viral load before IPT initiation
    Unsuppressed 6 (14.2) 1(6.2) 5 (19.2) 0.8
    Suppressed 13 (30.9) 3 (18.7) 10 (38.4)
    Not Documented 23 (54.7) 12 (75) 11 (42.3)
Viral load after IPT Initiation
    Unsuppressed 7 (16.6) 0 (0) 7 (26.9) 0.03
    Suppressed 27 (64.2) 12 (75) 15 (57.6)
    Not Documented 8 (19) 4 (25) 4 (15.3)
 Facility type
    Faith-based 13 (30.9) 4 (25) 9 (34.6) 0.07
    Public 26 (61.9) 9 (56.2) 17 (65.3)  
    Private 3 (7.1) 3 (18.7) 0 (0)  
 Routine screening
    Yes 41 (97.6) 15 (93.7)  26 (100) 0.2
    No 1 (2.4) 1 (6.3) 0
Clinic IPT initiated
    CCC 39 (92.8) 13 (81.2) 26 (100) 0.02
    OPD 3 (7.2) 3 (18.8) 0

TB–tuberculosis; IPT–isoniazid preventive therapy; CCC–comprehensive care clinics; OPD–out-patient department