Table 1. Comparison of UCD samples and healthy skin.

Ranka	Taxa	Control	Mild	P (M)	Severe	P (S)
P	Bacteroidetes	2.07	0.72	0.001	2.26	0.54
G	Bacteroides	0.22	0.07	0.04	0.50	0.60
G	Porphyromonas	0.04	0.17	0.07	0.75	0.01
S	Porphyromonas asaccharolytica	0.02	0.01	0.06	0.54	0.006
P	Fusobacteria	0.16	0.07	0.03	0.86	0.009
G	Fusobacterium	0.10	0.04	0.03	0.83	0.005
S	Fusobacterium necrophorum	0.03	0.01	0.03	0.78	0.002
P	Proteobacteria	17.27	8.23	0.002	5.03	<0.0001
P	Actinobacteria	50.55	60.78	0.07	77.04	0.06
G	Brachybacterium	1.43	0.58	0.23	0.17	0.0007
G	Brevibacterium	1.18	1.19	0.90	0.62	0.45
S	Brevibacterium luteolum	0.36	0.25	0.80	0.35	0.79
S	Brevibacterium sp. W0024	0.02	0.02	0.74	0.02	0.25
G	Bifidobacterium	5.52	1.51	0.02	0.32	0.0001
S	Bifidobacterium angulatum	1.01	0.11	0.03	0.05	0.002
G	Corynebacterium	11.68	27.06	0.02	37.96	0.0001
S	Corynebacterium camporealensis	0.33	0.50	0.10	0.60	0.02
S	Corynebacterium frankenforstense	1.18	0.63	0.46	0.33	0.04
S	Corynebacterium jeikeium	0.20	1.25	0.0007	0.62	<0.0001
S	Corynebacterium lactis	0.23	0.25	0.28	4.27	<0.0001
S	Corynebacterium sp. LMM-1652	0.05	0.24	0.001	0.17	<0.0001
S	Corynebacterium resistens	0.03	0.38	<0.0001	0.25	<0.0001
S	Corynebacterium urealyticum	0.10	0.24	0.04	0.77	<0.0001
S	Corynebacterium xerosis	1.10	0.84	0.26	1.69	0.88
G	Trueperella	0.17	0.12	0.17	2.87	<0.0001
S	Trueperella pyogenes	0.13	0.10	0.28	2.87	<0.0001
P	Firmicutes	27.31	23.99	0.68	10.47	0.002
G	Staphylococcus	1.40	2.86	0.14	1.08	0.91
S	Staphylococcus agnetis	0.005	0.008	0.21	0.007	0.27
S	Staphylococcus auricularis	0.12	1.28	0.18	0.11	0.57
S	Staphylococcus capitis	0.03	0.07	0.54	0.04	0.29
S	Staphylococcus chromogenes	0.01	0.03	0.32	0.04	0.36
S	Staphylococcus hominis	0.05	0.06	0.93	0.02	0.03

Bacterial phyla, genera and species representing at least 10% of the classified reads in at least one sample of samples from mild (M, n = 17) and severe (S, n = 19) udder cleft dermatitis (UCD) and 13 control (C) samples from cows without UCD. The 49 samples were obtained from 47 cows in six Swedish dairy herds. The median proportion of classified reads for each bacteria and sample type is presented. Differences in abundance between control samples and mild (M) UCD, and between control samples and severe (S) UCD samples were analyzed using the Wilcoxon rank sum test. A P-value ≤0.002 was considered significant due to multiple testing according to the Bonferroni correction.

^aP = Phylum, G = Genus, S = Species.