Table 2. Radiomics features of lymph nodes affected by sarcoidosis versus the features of lymph nodes affected by small cell carcinoma.
| Parameters | Sarcoidosis | Small cell carcinoma | P value | |
|---|---|---|---|---|
| Histogram (n = 30) | Skewness | -0.31 ± 0.63 | 0.05 ± 0.30 | N.S. |
| Kurtosis | 3.86 ± 1.87 | 3.60 ± 0.78 | N.S. | |
| Entropy_log10 | 0.69 ± 0.09 | 0.75 ± 0.09 | N.S. | |
| Entropy_log2 | 2.28 ± 0.30 | 2.48 ± 0.29 | N.S. | |
| Energy | 0.25 ± 0.04 | 0.22 ± 0.04 | N.S. | |
| GLCM (n = 30) | Homogeneity | 0.632 ± 0.046 | 0.584 ± 0.063 | 0.03 |
| Energy | 0.076 ± 0.025 | 0.057 ± 0.019 | N.S. | |
| Contrast | 1.647 ± 0.732 | 2.629 ± 1.501 | 0.016 | |
| Correlation | 0.470 ± 0.125 | 0.386 ± 0.098 | N.S. | |
| Entropy_log10 | 1.27 ± 0.15 | 1.41 ± 0.16 | 0.048 | |
| Entropy_log2 | 4.22 ± 0.50 | 4.67 ± 0.54 | 0.048 | |
| Dissimilarity | 0.927 ± 0.207 | 1.174 ± 0.342 | 0.018 | |
| GLRLM (n = 30) | SRE | 0.756 ± 0.046 | 0.795 ± 0.052 | N.S. |
| LRE | 2.88 ± 0.59 | 2.44 ± 0.51 | 0.048 | |
| HGRE | 4911.8 ± 131.5 | 4796.8 ± 125.8 | 0.009 | |
| SRHGE | 3713.3 ± 254.7 | 3815.4 ± 291.1 | N.S. | |
| LRHGE | 14159.4 ± 2930.5 | 11665.2 ± 2434.4 | 0.028 | |
| GLNU | 29.2 ± 3.4 | 27.9 ± 3.2 | N.S. | |
| RLNU | 71.5 ± 13.8 | 85.9 ± 20.7 | N.S. | |
| RP | 0.692 ± 0.052 | 0.739 ± 0.062 | N.S. | |
| NGLDM (n = 30) | Coarseness | 0.042 ± 0.006 | 0.040 ± 0.005 | N.S. |
| Contrast | 0.040 ± 0.010 | 0.047 ± 0.019 | N.S. | |
| Busyness | 873×10−3 ± 0.592 | 622×10−3 ± 0.259 | N.S. | |
| GLZLM (n = 30) | SZE | 0.479 ± 0.118 | 0.551 ± 0.967 | N.S. |
| LZE | 86.72 ± 62.58 | 46.56 ± 29.20 | 0.046 | |
| HGZE | 4896.0 ± 141.5 | 4803.4 ± 124.0 | N.S. | |
| SZHGE | 2340.8 ± 587.9 | 2651.8 ± 481.6 | N.S. | |
| LZHGE | 427349.3 ± 308783.4 | 222578.6 ± 139458.0 | 0.038 | |
| GLNUz | 7.8 ± 1.7 | 9.2 ± 1.7 | 0.041 | |
| ZLNU | 12.5 ± 6.7 | 19.5 ± 12.2 | N.S. | |
| ZP | 0.240 ± 0.074 | 0.312 ± 0.101 | N.S. | |
| EBUS (n = 19) | FLR | 4.12 ± 2.04 | 33.65 ± 40.79 | 0.013 |
Abbreviations: N.S. = not significant. GLCM = gray-level co-occurrence matrix. GLRLM = gray-level run length matrix. SRE = short-run emphasis. LRE = long-run emphasis. HGRE = high gray-level emphasis. SRHGE = short-run high gray-level emphasis. LRHGE = long-run high gray-level emphasis. GLNU = gray-level non-uniformity for run. RLNU = run length non-uniformity. RP = run percentage. NGLDM = neighborhood gray-level different matrix. GLZLM = gray-level zone length matrix. SZE = short-zone emphasis. LZE = long-zone emphasis. HGZE = high gray-level zone emphasis. SZHGE = short-zone high gray-level emphasis. LZHGE = long-zone high gray-level emphasis. GLNUz = gray-level non-uniformity for zone. ZLNU = zone length non-uniformity. ZP = zone percentage. EBUS = endobronchial ultrasound. FLR = fat-to-lesion strain ratio.