Table 1. Main characteristics of the eligible studies.
| Study | Patients’ country | Published year | Size Case/control | Gender(male) Case/control | Age (years) Case/control | ICH | Diagnosis | Specimen type | Diagnosing method | NOS score |
|---|---|---|---|---|---|---|---|---|---|---|
| Shiratori B | Japan | 2014 | 37/30 | 23/9 | 39.5±9.88/34.5±9.07 | HIV (-) | PTB | Plasma | AFB staining, clinical symptoms and chest radiographs | 7 |
| Shiratori B | Japan | 2017 | 36/19 | 28/12 | 56.0±15.84/38.5±13.00 | HIV (-) | PTB | Plasma | Culture | 5 |
| Inomata SI | Japan | 2003 | 47/25 | NA/16 | NA/23-62 | None | PTB | Plasma | Culture or histologically proven | 5 |
| Zhang YT | China | 2018 | 48/53 | 32/36 | 36.1±9.7/35.3±10.2 | None | PTB | Serum | NR | 5 |
| Wu TF | China | 2017 | 51/63 | 21/29 | 41.85±11.55/39.73±10.06 | None | Spinal tuberculosis | Serum | Histopathology | 7 |
| Ding YL | China | 2017 | 20/20 | 13/NA | 55.0±19.8/45.0±21.9 | None | PTB | Plasma | AFB staining | 8 |
| Hao XL | China | 2016 | 43/40 | 23/20 | 40.5±6.5/38.9±5.8 | None | Smear-negative PTB | Serum | Histopathology | 8 |
| Cui JX | China | 2014 | 80/100 | 54/67 | 44.6±12.3/41.9±10.6 | NR | PTB | Serum | NR | 7 |
| Guo SX | China | 2013 | 42/36 | 31/28 | 34.6±10.1/31.2±8.6 | None | PTB | Serum | NR | 7 |
| Gan B | China | 2009 | 44/20 | 28/14 | 39.5±13.67/30.5±9.10 | None | TB | Plasma | NR | 6 |
| Du H | China | 2020 | 50/20 | 37/14 | 52.6±10.7/49.8±11.2 | None | PTB | Serum | AFB staining | 8 |
| Wang Q | China | 2019 | 92/50 | 52/31 | 43.68±9.84/43.19±9.76 | None | PTB | Serum | NR | 7 |
| Wu YX | China | 2019 | 90/90 | 56/51 | 49.6±17.2/47.6±18.2 | None | PTB | Serum | PPD skin test, AFB staining, chest radiographs, etc. | 7 |
| Feng PL | China | 2017 | 55/60 | 38/41 | 35.7±9.5/36.1±8.6 | None | PTB | Serum | NR | 5 |
| Yuan Y | China | 2016 | 52/45 | 36/35 | 35.5±11.2/32.2±9.7 | None | PTB | Serum | NR | 5 |
| Qiao YF | China | 2013 | 62/35 | 44/22 | 41.9±10.5/41.2±10.7 | None | PTB | Serum | NR | 5 |
| Sun XX | China | 2016 | 84/80 | 65/41 | 57.72±16.43/56.95±19.37 | None | PTB | Serum | Histopathology | 6 |
ICH, immune-compromised host; HIV, human immunodeficiency virus; NA, not available; NR, not reported; PTB, pulmonary tuberculosis; TB, tuberculosis; AFB staining, acid-fast bacilli staining; PPD, purified protein derivative; NOS, Newcastle-Ottawa Scale.