Fig 3. Cftr is expressed in endocrine cells of the mouse islet.

A-J. Immunofluorescence images of WT mouse (Cftr^WT) pancreas immunostained with the Cftr antibody acl-006 [(Table 1), A and F] in combination with antibodies against insulin (Ins, B), glucagon (Glc, C), somatostatin (Stt, H) and pancreatic polypeptide (PP, G). Magnified overlay images of D and I are shown in E and J, respectively, wherein Cftr immunoreactivity in α-, β-, δ- and PP-cells of the mouse islet is indicated by arrows. K-L. Immunohistochemistry images of normal human pancreas immunostained with acl-006. The islet encircled by a dashed red trace in K is magnified in L to show CFTR immunoreactivity. Bars in A-G represent 25μm.