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A schematic diagram showing the role of miR‐25‐3p derived from ADMSC‐EVs in a preclinical stroke model. ADMSCs release EVs enriched with miR‐25‐3p, which are uptaken by neurons. In neurons, miR‐25‐3p induces degradation of the mRNA of p53, resulting in the downregulation of the p53 protein level and subsequent reduction of BNIP3. The inhibition of BNIP3, in turn, further reduces the levels of autophagy which exerts the neuroprotective effect
