Table 2.
Feature | OverallN = 101 | Unfavourable clinical evolutionN = 44 | Undefined clinical EvolutionN = 11 | Favourable clinical EvolutionN = 46 | P value |
Age(years) | 53 (IQR = 17) | 51.5 (IQR = 18.25) | 50 (IQR = 12.5) | 55 (IQR = 19.75) | .16 |
Race (%) | |||||
Non-Caucasian | 66 (65.3) | 28 (27.7) | 6 (5.9) | 32 (31.7) | .61 |
Caucasian | 35 (34.7) | 16 (15.8) | 5 (5) | 14 (13.9) | |
Sex | |||||
female | 69 (68.3) | 32 (31.7) | 6 (5.9) | 31 (30.7) | .45 |
male | 32 (31.7) | 12 (11.9) | 5 (5) | 15 (14.9) | |
Smoking (current or past) | |||||
no | 72 (72.7) | 33 (32.7) | 8 (7.9) | 31 (30.7) | .73 |
yes | 27 (27.3) | 10 (9.9) | 3 (3) | 14 (13.9) | |
Diagnostic Age (years) | 44 (IQR = 17) | 44.5 (IQR = 16.25) | 50 (IQR = 13) | 41.5 (IQR = 17.75) | .42 |
Radiological Staging (%) | |||||
1 | 14 (13.9) | 4 (4) | 0 (0) | 10 (9.9) | .26 |
2 | 52 (51.5) | 25 (24.8) | 7 (6.9) | 20 (19.8) | |
3 | 17 (16.8) | 6 (5.9) | 1 (1) | 10 (9.9) | |
4 | 18 (17.8) | 9 (8.9) | 3 (3) | 6 (5.9) | |
Rheumatological markers - ANA, RF or ANCA (%) | |||||
negative | 70 (76.9) | 27 (26.7) | 9 (8.9) | 34 (33.7) | .21 |
positive | 21 (23.1) | 13 (12.9) | 1 (1) | 7 (6.9) | |
Pulmonary arterial hypertension | |||||
no | 92 (96.8) | 39 (38.6) | 10 (9.9) | 43 (42.6) | .72 |
yes | 3 (3.2) | 2 (2) | 0 (0) | 1 (1) | |
FEV1 (%)∗ | 83 (IQR = 23.5) | 75 (IQR = 25.5) | 84 (IQR = 24) | 86 (IQR = 15.75) | .002 |
FEV1/FVC (%)∗ | 80.5 (IQR = 11) | 80 (IQR = 10) | 82 (IQR = 6.5) | 80 (IQR = 11.75) | .82 |
FVC (%)∗ | 83.5 (IQR = 24.25) | 79 (IQR = 20.5) | 81 (IQR = 16) | 93.5 (IQR = 19.5) | .001 |
Pulmonary tests∗ | |||||
within the predicted | 51 (51) | 15 (14.9) | 5 (5) | 31 (30.7) | .007 |
Impaired | 49 (49) | 28 (27.7) | 6 (5.9) | 15 (14.9) |