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Clinical manifestations reported as initial symptoms by patients.
| Early clinical manifestations | N (%) |
| Respiratory∗ | 62 (61) |
| Skin | 46 (45) |
| Constitutional symptoms† | 23 (22) |
| Asymptomatic | 11 (10) |
| Ophthalmologic | 10 (9) |
| Cardiology‡ | 6 (6) |
| Peripheral lymph node enlargement | 3 (3) |
| Parotid gland | 2 (2) |
| Neurology§ | 2 (2) |
| Queilitis | 1 (1) |
| Nephrotic syndrome | 1 (1) |
