Figure 7. aPDT with 1D9-700DX in combination with KI in the presence of plasma.

Photoactivated killing of CA-MRSA AH4807 grown to exponential phase (~1 × 10⁷ CFU/mL), in the presence or absence of plasma, upon treatment with or without 3.3 μM of 1D9-700DX and with or without 50 mM of KI. Bacteria were treated with red light at a radiant exposure of 30 J.cm^–2 (+) or kept in the dark (–). (A and B) Numbers of surviving bacteria (Log₁₀[CFU/mL]) and monitoring of the formation of iodine at 340 nm are represented in A and B, respectively. Data are presented as mean ± SEM of 3 experiments performed in triplicate. Ordinary 1-way ANOVA tests with subsequent Dunnett’s multiple-comparison tests were used for statistical analysis. Significant differences compared with the negative control group (no 1D9-700DX and no light) are marked as follows: ****P < 0.0001.