Figure 8. MS patients with contracting ventricles have lower disease severity and duration.

(A and B) MS patients who showed contractions (n = 24) in ventricle volumes greater than 6% had significantly lower disease severity at the study baseline, as indicated by the Expanded Disability Status Scale, EDSS) (**P = 0.0221, Mann-Whitney test) (A), and significantly lower median EDSS during the study period (**P = 0.0063, Mann-Whitney test) (B). (C) The patients with ventricle contractions also had significantly shorter total disease duration (***P = 0.046, Student’s t test). (D–F) There were no significant differences between contracting and noncontracting patients (n = 9) in volume of CEL (D), T₂ (E), or BH lesions (F) over the course of the study.