Table 4.

Topological analysis results by degree—the first 32 proteins.

Gene names	Annotation	Degree	Betweenness
NTRK1	Neurotrophic receptor tyrosine kinase 1	239	79.2792394
EGFR	Epidermal growth factor receptor	170	57.27745249
FN1	Fibronectin	169	36.34401789
UBC	Ubiquitin C	157	50.80248406
PPARG	Peroxisome proliferator-activated receptor gamma	153	37.99948007
ESR1	Estrogen receptor 1	150	113.2071674
HSP90AA1	Heat shock protein 90 alpha family class A member 1	132	103.9892463
VCP	Valosin-containing protein	121	53.86564087
YWHAZ	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta	119	64.36717285
MYC	v-myc avian myelocytomatosis viral oncogene homolog	112	77.51063594
HSPA5	Heat shock protein family A (Hsp70) member 5	108	34.49237132
NPM1	Nucleophosmin	106	63.99301971
HSP90AB1	Heat shock protein 90 alpha family class B member 1	104	52.53742327
COPS5	COP9 signalosome subunit 5	102	84.17298609
EP300	E1A-binding protein p300	98	59.70375531
SRC	SRC protooncogene, nonreceptor tyrosine kinase	94	52.01196867
AR	Androgen receptor	93	39.60526919
BRCA1	BRCA1, DNA repair associated	92	37.41150073
MDM2	MDM2 protooncogene	88	56.58152297
AKT1	AKT serine/threonine kinase 1	87	57.04410728
CTNNB1	Catenin beta 1	85	44.34296823
HSPA4	Heat shock protein family A (Hsp70) member 4	83	59.0919423
EEF1A1	Eukaryotic translation elongation factor 1 alpha 1	81	44.07432309
SMAD2	SMAD family member 2	78	38.64577814
RELA	RELA protooncogene, NF-κB subunit	77	40.34807667
NFKB1	Nuclear factor kappa B subunit 1	75	41.54441528
TUBB	Tubulin beta class I	72	85.09134103
IKBKG	Inhibitor of nuclear factor kappa B kinase subunit gamma	69	40.75351178
HNRNPA1	Heterogeneous nuclear ribonucleoprotein A1	67	45.38051383
PRKDC	Protein kinase, DNA-activated, catalytic polypeptide	66	45.37484081
ABL1	ABL protooncogene 1, nonreceptor tyrosine kinase	65	34.38427075
STUB1	STIP1 homology and U-box-containing protein 1	64	41.4704054