Table 5.

Gene sets enriched in high phenotype.

Description	Set size	Enrichment score	NES	NOM p value	p adjust	FDR q values	Rank	Leading_edge
Reactome_synthesis_of_leukotrienes_LT_and_eoxins_EX	21	0.794	2.602	0.004	0.060	0.045	4526	Tags = 57%, list = 8%, signal = 52%
Biocarta_inflam_pathway	27	0.695	2.434	0.005	0.060	0.045	6632	Tags = 63%, list = 12%, signal = 55%
Reactome_heparan_sulfate_heparin_HS_GAG_metabolism	55	0.391	1.639	0.008	0.068	0.051	9176	Tags = 44%, list = 17%, signal = 36%
KEGG_hematopoietic_cell_lineage	84	0.609	2.813	0.010	0.069	0.051	7667	Tags = 61%, list = 14%, signal = 52%
Reactome_collagen_formation	90	0.467	2.138	0.012	0.071	0.053	3536	Tags = 36%, list = 7%, signal = 33%
Reactome_MHC_class_II_antigen_presentation	122	0.325	1.545	0.019	0.092	0.069	8284	Tags = 26%, list = 15%, signal = 22%

NES: normalized enrichment score; NOM: nominal; FDR: false discovery rate. Gene sets with NOM p value < 0.05 and FDR q value < 0.05 are considered as significant.