Table 2.
The top 20 lncRNAs with significant differential expression in white blood cells from both T1D patients and healthy controls.
| Gene | C normalize | T1D normalize | Log2 fold change | FDR | Up/down | Gene name | Biotype | Position |
|---|---|---|---|---|---|---|---|---|
| ENSG00000273338 | 107.87 | 8.48 | -3.67 | 7.91688E − 07 | Down | RP11-386I14.4 | Antisense | chr1:78004346-78004554:- |
| ENSG00000270069 | 433.51 | 76.07 | -2.51 | 8.65909E − 06 | Down | MIR222HG | lincRNA | chrX:45745211-45770274:- |
| ENSG00000269902 | 86.55 | 13.28 | -2.70 | 0.000138695 | Down | RP6-99M1.3 | lincRNA | chrX:45764772-45765299:- |
| MSTRG.74858 | 80.41 | 9.89 | -3.02 | 0.000569468 | Down | — | linc | chr17:83203319-83204570:+ |
| MSTRG.49388 | 15.38 | 0.32 | -5.60 | 0.000600013 | Down | — | linc | chr13:88709424-88744650:+ |
| MSTRG.185495 | 1.27 | 18.66 | 3.88 | 0.000619542 | Up | — | linc | chr9:128668273-128670326:- |
| ENSG00000267174 | 50.40 | 401.59 | 2.99 | 0.00066093 | Up | CTC-510F12.4 | 3prime_overlapping | chr19:11300777-11324441:- |
| MSTRG.182419 | 91.26 | 17.30 | -2.40 | 0.000702034 | Down | — | linc | chr9:91193131-91198833:+ |
| MSTRG.180334 | 0.62 | 13.17 | 4.41 | 0.000704429 | Up | — | linc | chr9:61465105-61467945:+ |
| MSTRG.71335 | 23.50 | 100.09 | 2.09 | 0.000976723 | Up | — | linc | chr17:42195078-42198266:- |
| MSTRG.111791 | 28.91 | 116.47 | 2.01 | 0.000979217 | Up | — | linc | chr22:41419090-41428731:+ |
| MSTRG.125714 | 9.04 | 50.39 | 2.48 | 0.001001754 | Up | — | Antisense | chr3:196215032-196228373:- |
| MSTRG.161229 | 28.27 | 137.55 | 2.28 | 0.001011298 | Up | — | Antisense | chr7:27102269-27107589:+ |
| MSTRG.73913 | 0.15 | 8.82 | 5.90 | 0.001038576 | Up | — | Antisense | chr17:75346002-75347825:+ |
| MSTRG.10587 | 4.81 | 30.79 | 2.68 | 0.001351147 | Up | — | Antisense | chr1:156211503-156218677:- |
| MSTRG.147880 | 0.19 | 15.30 | 6.31 | 0.001402952 | Up | — | linc | chr5:178650106-178668781:- |
| MSTRG.95087 | 97.19 | 17.17 | -2.50 | 0.00144056 | Down | — | linc | chr2:144660953-144665439:+ |
| MSTRG.103146 | 618.92 | 214.32 | -1.53 | 0.001589855 | Down | — | Antisense | chr20:17570371-17583003:+ |
| MSTRG.5412 | 50.35 | 311.44 | 2.63 | 0.001609361 | Up | — | linc | chr1:65034964-65038215:- |
| MSTRG.80841 | 1.09 | 13.82 | 3.67 | 0.001677829 | Up | — | linc | chr19:10959257-10960669:- |