. Author manuscript; available in PMC: 2021 Dec 1.

Published in final edited form as: Cancer Epidemiol. 2020 Sep 30;69:101826. doi: 10.1016/j.canep.2020.101826

Table 4.

Conditional logistic regression to assess the relationship between metabolite risk score associated with breast cancer risk

	Model 1^*		Model 2^#

	OR (95%CI)	P value	OR (95%CI)	P value
Continuous variable	1.72 (1.46–3.70)	<0.001	1.67 (1.32–3.94)	<0.001
Stratified by time between blood collection and cancer diagnosis
≤ 5 years	1.90 (1.27, 4.89)	0.003	1.84 (1.15, 4.78)	0.011
> 5 years	1.49 (1.04, 5.02)	0.044	1.43 (1.02, 5.16)	0.047
Categorical variable
Low (0–1)	Reference		Reference
High (2–3)	3.91 (1.87, 10.32)	<0.001	3.82 (1.78–11.56)	<0.001
Stratified by time between blood collection and cancer diagnosis
≤ 5 years	5.55 (1.65, 13.58)	<0.001	5.38 (1.62, 13.57)	<0.001
≤ 5 years	2.47 (1.08, 15.06)	0.028	2.36 (1.07, 14.85)	0.030

^*.

Adjusted by parity, education, birth place, language acculturation, and BMI category.

^#.

Adjusted by parity, education, birth place, language acculturation, and BMI category, smoking status, alcohol status, sitting time, and physical activity.