Table 3.
Physical Activity and Symptom Descriptives
| Variable | Unadjusted Means (SD) | p-value | Unadjusted Means (SD) | p-value | ||||
|---|---|---|---|---|---|---|---|---|
| Overall | Model 1 | Model 2 | T1 (a) | T2 (b) | T3 (c) | Model 1 | Model 2 | |
| Daily Symptom | ||||||||
| Affect | 2.88 (2.09) | 2.71 (2.08)c | 2.95(2.09) | 3.01 (2.10)a | 0.03 | 0.01 | ||
| Pre-CT Dose | 2.01(1.90) | <0.001 | <0.001 | 1.83( (1.96) | 1.95 (1.81) | 2.31 (1.88) | 0.34 | 0.13 |
| Day-of/Post-CT Dose | 3.24 (2.07) | 3.09 (2.01) | 3.35 (2.06) | 3.31 (2.12) | ||||
| Anxiety | 1.88 (0.94) | 1.96(0.98) | 1.84 (0.92) | 1.93 (0.95) | 0.63 | <0.01 | ||
| Pre-CT Dose | 1.79 (0.88) | <0.01 | 0.03 | 1.90 (0.93) | 1.64 (0.77) | 1.84 (0.92) | 0.01 | 0.05 |
| Day-of/Post-CT Dose | 1.91 (0.96) | 1.98 (1.00) | 1.78 (0.90) | 1.97 (0.96) | ||||
| Depression | 1.43 (0.61) | 1.43 (0.61) | 1.40 (0.59) | 1.44 (0.63) | 0.77 | <0.001 | ||
| Pre-CT Dose | 1.35 (0.56) | <0.001 | <0.001 | 1.31 (0.52) | 1.35 (0.55) | 1.40 (0.62) | <0.01 | 0.01 |
| Day-of/Post-CT Dose | 1.46 (0.63) | 1.48 (0.63) | 1.43 (0.61) | 1.46 (0.64) | ||||
| Fatigue | 2.15 (0.74) | 2.09 (0.69)c | 2.14 (0.73)c | 2.21 (0.78)a,b | 0.01 | 0.05 | ||
| Pre-CT Dose | 1.86 (0.66) | <0.001 | <0.001 | 1.76 (0.62) | 1.86 (0.66) | 2.00 (0.69) | <0.001 | 0.04 |
| Day-of/Post-CT Dose | 2.26 (0.74) | 2.23 (0.68) | 2.26 (0.73) | 2.30 (0.80) | ||||
| Physical Function-ADL | 1.74 (0.89) | 1.64 (0.84)c | 1.56 (0.81) | 1.81 (0.94)a | <0.001 | <0.001 | ||
| Pre-CT Dose | 1.44 (0.70) | <0.001 | <0.001 | 1.33 (0.60) | 1.46 (0.66) | 1.56 (0.82) | 0.91 | 0.40 |
| Day-of/Post-CT Dose | 1.86 (0.93) | 1.77 (0.89) | 1.90 (0.94) | 1.92 (0.97) | ||||
| Physical Function-Walk | 1.73 (0.92) | 1.57 (0.78)b,c | 1.81 (1.00)a | 1.81 (0.95)a | <0.001 | <0.001 | ||
| Pre-CT Dose | 1.39 (0.72) | <0.001 | <0.001 | 1.21 (0.47) | 1.46 (0.81) | 1.54 (0.80) | 0.48 | 0.49 |
| Day-of/Post-CT Dose | 1.86 (0.96) | 1.71 (0.83) | 1.96 (1.03) | 1.93 (0.98) | ||||
| Pain | 1.62 (2.05) | 1.34 (1.84)c | 1.71 (2.06)a | 1.86 (2.24)a | 0.02 | 0.23 | ||
| Pre-CT Dose | 1.19 (1.98) | <0.001 | <0.001 | 0.82 (1.61) | 1.24 (1.95) | 1.60 (2.31) | 0.30 | 0.88 |
| Day-of/Post-CT Dose | 1.79 (2.06) | 1.55 (1.88) | 1.90 (2.08) | 1.97 (2.21) | ||||
| Cognitive Function | 2.05 ((0.91) | 2.02 (0.88) | 2.03 (0.91) | 2.11 (0.94) | 0.35 | 0.73 | ||
| Pre-CT Dose | 1.89(0.89) | <0.001 | <0.001 | 1.81(0.85) | 1.90 (0.93) | 1.96 (0.89) | 0.04 | 0.15 |
| Day-of/Post-CT Dose | 2.11 (0.91) | 2.10 (0.89) | 2.07 (0.90) | 2.17 (0.95) | ||||
| Daily Activity Intensities (mins) | ||||||||
| MVPA | 22.74 (27.57) | 22.22 (21.87)c | 22.39 (26.85) | 23.78 (33.85)a | 0.45 | <0.001 | ||
| Pre-CT Dose | 26.28 (24.22) | <0.01 | <0.001 | 27.07 (23.68) | 27.08 (25.89) | 24.43 (22.89) | 0.01 | 0.60 |
| Day-of/Post-CT Dose | 21.25 (28.73) | 20.32 (2.39) | 20.48 (27.00) | 23.50 (37.51) | ||||
| Light Physical Activity | 228.44 (92.64) | 226.66 (81.15)b,c | 230.41 (99.45)a | 228.36 (97.62)a | <0.001 | <0.001 | ||
| Pre-CT Dose | 238.41 (89.33) | <0.01 | <0.001 | 245.50 (83.04) | 238.20 (96.36) | 229.83 (88.19) | <0.001 | <0.001 |
| Day-of/Post-CT Dose | 224.24 (93.69) | 218.48 (78.96) | 227.25 (100.54) | 227.74 (101.34) | ||||
Note: CT= Chemotherapy; Values in bold indicate significant group difference. Model 1 examined time point and treatment status independently except for the interaction model which included both time point and treatment status and the time point*treatment status interaction. Model 2 included time point, treatment status, time point*treatment status interaction and relevant covariates including age, BMI, number of comorbidities, health status, disease stage, type of chemotherapy (neoadjuvant v. adjuvant), weekend day, and treatment cycle number. All physical activity models controlled for wear time.
Comparison between time points where a= time point 1; b= time point 2; c=time point 3 and indicate significance between groups at p<0.017 when controlling for covariates, treatment status and time point*treatment status interaction.