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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: Clin Cancer Res. 2020 Sep 1;26(23):6350–6361. doi: 10.1158/1078-0432.CCR-20-1497

Figure 1. Diagrams representing CNApp broad and focal score distributions and their correlation with the ESTIMATE immunity score in a pan-cancer cohort.

Figure 1.

(A) Broad score distribution across 33 cancer types from the TCGA. (B) Dot-plots displaying the correlation between broad score and ESTIMATE-derived immune score per cancer type. (C) Focal score distribution across 33 cancer types from the TCGA. (D) Dot-plot with focal score and immune score correlations per cancer type. P: spearman correlation p-value; R: Spearman regression coefficient. Arrow in (A) and (C) and box in (B) and (D) indicate HCC. TCGA cancer project abbreviations: LAML, Acute Myeloid Leukemia; THCA, Thyroid Carcinoma; PRAD, Prostate Adenocarcinoma; UCEC, Uterine Corpus Endometrial Carcinoma; LGG, Brain Lower Grade Glioma; PAAD, Pancreatic Adenocarcinoma; KIRC, Kidney Renal Clear Cell Carcinoma; PCPG, Pheochromocytoma and Paraganglioma; STAD, Stomach Adenocarcinoma; GBM, Glioblastoma Multiforme; KIRP, Kidney Penal Papillary Cell Carcinoma; BRCA, Breast Invasive Carcinoma; BLCA, Bladder Urothelial Carcinoma; CESC, Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma; HNSC, Head and Neck Squamous Cell Carcinoma; LIHC, Liver Hepatocellular Carcinoma; LUAD, Lung Adenocarcinoma; SKCM, Skin Cutaneous Melanoma; COAD, Colon Adenocarcinoma; ESCA, Esophageal Carcinoma; LUSC, Lung Squamous Cell Carcinoma; OV, Ovarian Serous Cystadenocarcinoma; READ, Rectum Adenocarcinoma; UCS, Uterine Carcinosarcoma; ACC, Adrenocortical Carcinoma; KICH, Kidney Chromophobe Cell Carcinoma.