TABLE 3.
Association of progression-free and overall survival with prognostic factors using univariate log-rank test
| Progression-free survival |
Overall survival |
||||
|---|---|---|---|---|---|
| Variables | Total | HR | P | HR | P |
| LNmM | |||||
| Absent | 103 | 1 | 0.93 | 1 | 0.91 |
| Present | 26 | 1.07 | 1.09 | ||
| Tumor size | |||||
| <2 | 50 | 1 | 0.59 | 1 | 0.54 |
| 2–3.9 | 54 | 0.9 | 0.79 | ||
| ≥4 | 25 | 1.85 | 1.78 | ||
| LVSI | |||||
| Absent | 82 | 1 | 0.059 | 1 | 0.16 |
| Present | 47 | 3.08 | 2.21 | ||
| Margin | |||||
| Negative/close | 116 | 1 | 0.002 | 1 | 0.001 |
| Positive | 13 | 6.11 | 6.48 | ||
| Stage | |||||
| 1A2 | 10 | 1 | 0.46 | 1 | 0.22 |
| 1B1 | 106 | 0.71 | 0.37 | ||
| 1B2 | 13 | 1.84 | 1.07 | ||
| Grade | |||||
| 1 | 52 | 1 | 0.44 | 1 | 0.81 |
| 2 | 48 | 1.6 | 1.19 | ||
| 3 | 29 | 0.47 | 0.71 | ||
| Cervical stromal invasion | |||||
| Middle/outer | 61 | 1 | 0.36 | 1 | 0.47 |
| Inner | 59 | 0.4 | 0.5 | ||
| None | 9 | 1.17 | 1.29 | ||
| Parametrial involvement | |||||
| Absent | 114 | 1 | 0.33 | 1 | 0.064 |
| Present | 15 | 2.11 | 3.21 | ||
| Postoperative radiation therapy | |||||
| No | 100 | 1 | 0.16 | 1 | 0.15 |
| Yes | 29 | 2.33 | 2.35 | ||
| Chemotherapy | |||||
| No | 17 | 1 | 0.36 | 1 | 0.28 |
| Yes | 13 | 1.28 | 1.62 | ||
| NA | 99 | 0.49 | 0.53 | ||
Adjuvant therapy was at the discretion of the treating clinician. NA were patients not meeting criteria for further therapy.
HR indicates hazard ratio; LNmM, lymph node micrometastasis; LVSI, lymphovascular space invasion.