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. 2020 Dec 2;11:6161. doi: 10.1038/s41467-020-20001-w

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a Scatter plots showing correlation of gene-body 5hmC levels with gene expression levels. R represents the Pearson correlation coefficient, and ρ represents the Spearman correlation coefficient. b Correspondence at the top (CAT) plot showing percentages of gene overlap against top percentages of 5hmC-modified genes and expressed genes. Diagonal dashed line represents results from two random gene sets, and the horizontal dashed line represents results from two exact gene sets. c Subtractions of covered transcription factors for top 10% 5hmC-modified genes and top 10% highly expressed genes. d Heatmaps showing correlation of gene-body 5hmC levels with gene-body H3K36me3 levels. TSS, transcription start site. TES, transcription end site. e Subtractions of covered tissue-specific expressed genes for top 10% 5hmC-modified genes and top 10% H3K36me3-modified genes.

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