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. 2020 Dec 2;11:6161. doi: 10.1038/s41467-020-20001-w

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a Heatmaps showing correlation of 5hmC and H3K27ac signals at all enhancers in 8 representative tissue types. b Subtractions of covered tissue-specific enhancers for the top 10% 5hmC-modified enhancers and the top 10% H3K27ac-modified enhancers. c Subtractions of covered ubiquitous enhancers for the top 10% 5hmC-modified enhancers and the top 10% H3K27ac-modified enhancers. d Heatmaps showing correlation of 5hmC and H3K4me1 signals at all enhancers in 8 representative tissue types. e Subtractions of covered tissue-specific enhancers for the top 10% 5hmC-modified enhancers and the top 10% H3K4me1-modified enhancers. f Subtractions of covered ubiquitous enhancers for the top 10% 5hmC-modified enhancers and the top 10% H3K4me1-modified enhancers.

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