Table 2.

MIC₅₀ values for garvicin KS and micrococcin P1 determined in biofilms for the indicated strains.

Antimicrobial (mg/ml)	Strain
	ATCC 10832	Newman	USA 300	ATCC 29213	ATCC 33591	S.a. 3255
Individual components
Garvicin KS	2.5	1.25	2.5	1.25	>5	1.25
Micrococcin P1	>1.0 × 10−1	>1.0 × 10−1	>1.0 × 10−1	>1.0 × 10−1	>1.0 × 10−1	>1.0 × 10−1
Combination
Garvicin KS	1.25	1.25	5	1.25	>5	3.1×10−1
Micrococcin P1	2.5 × 10−2	2.5 × 10−2	1.0 × 10−1	2.5 × 10−2	>1.0 × 10−1	2.5 × 10−2
FICa	0.75	1.25	1.5	1.25	NDb	0.5

^aSynergy achieved with fractional inhibition concentration (FIC) ≤ 0.5.

^bNot determined. The MIC values exceeded the maximum concentration tested: micrococcin P1, 1.0 × 10⁻¹ mg/ml; garvicin KS, 5 mg/ml.