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. 2020 Nov 19;11:573214. doi: 10.3389/fphys.2020.573214

TABLE 2.

Allele frequencies and details of WNT10A c.511C > T (p.Arg171Cys) and c.637G > A (p.Gly213Ser) variants.

rs116998555 c.511C > T (p.Arg171Cys)
rs147680216 c.637G > A (p.Gly213Ser)
Database Allele count Allele number Number of homozygotes Allele frequency Allele count Allele number Number of homozygotes Allele frequency
gnomAD (v2.1.1 and v3)
East Asian 370 23084 3 0.016 657 22960 16 0.029
Non-East Asian 335 402864 1 0.001 22 400838 0 0.000
    South Asian 51 33652 1 0.002 4 33616 0 0.000
    African 32 67004 0 0.001 3 66550 0 0.000
    Ashkenazi Jewish 0 13692 0 0.000 0 13646 0 0.000
    European (Finnish) 13 35558 0 0.000 0 35046 0 0.000
    European (non-Finnish) 223 193594 0 0.001 4 192768 0 0.000
    Latino 6 49094 0 0.000 3 48994 0 0.000
    Other 10 10270 0 0.001 8 10218 0 0.001
Total 705 425948 4 0.002 679 423798 16 0.002
GenomeAsia 100K
Southeast Asia 4 692 0 0.006 3 692 0 0.004
Northeast Asia 5 702 0 0.007 10 702 0 0.014
South Asia 7 1448 0 0.005 0 1448 0 0.000
Other 0 636 0 0.000 0 636 0 0.000
Total 16 3478 0 0.005 13 3478 0 0.004
Northeast Asian Reference Database (NARD) 35 3558 NA 0.010 51 3558 NA 0.014
Han Chinese genome project (PGG.Han) 3596 107232 NA 0.033 1161 108146 NA 0.011
4.7K JPN (4,773 Japanese individuals) NA NA NA 0.010 NA NA NA 0.015
HGVD (3,248 Japanese individuals) 36 2412 0 0.015 35 2388 0 0.015
Korean Variant Archive (KOVA) (1,055 healthy Korean individuals) NA NA NA 0.019 NA NA NA 0.019
ThWES 1876 (In-house database of 1,876 Thai individuals) 58 3752 4 0.016 59 3752 0 0.016

JPN, Japanese individual genome variation; genomAD, Genome Aggregation Database; HGVD, Human Genetic Variation Database; NA, not available. Bold numbers indicate maximum and minimum allele frequencies in the column.