Table 3.

Description of graph analysis metrics.

Global Metric	Description
Network density	Fraction of all possible connections above the connection threshold
Mean connection strength	Average connection strength of connections above the connection threshold
Clustering Coefficient	Extent of node clustering; a measure of how often the neighbors of a node are also neighbors of each other
Path Length	Lowest number of connections required to travel between each node pair in the network
Modularity score	Ability of the network to be segregated into discrete modules
Nodal Metric	Description
Node strength	Sum of the strength of connections to all other nodes in the network
Closeness centrality	Nearness to all other nodes in the network
Betweenness centrality	Frequency at which the node lies on the shortest path between two other nodes
Within-module degree Z-score	Connectedness of a node within its own module
Participation coefficient	Connectedness of a node to nodes in other modules