Fig. 2.

Macroscopically, the tumor from the left lobe was around 17 cm in diameter with irregular multinodular lesions and intra-capsular grey to white tumor (a). The tumor from the right thyroid lobe was 6 cm in diameter and enlargement of multiple lymph nodes (range 0.8–3.2 cm in diameter, panel a). Polymorphic and enlarged tumor cells with round nuclei, coarse chromatin, prominent nucleoli forming a ground glass appearance (b). Infiltration to thyroid capsule (c), veins (b), lymphatic vessels, surrounding skeletal muscles and soft tissues were also observed.