Table 3.
CAN parameters before and after vitamin D supplementation in patients with T1DM.
| Parameters | N=23 | p | |
|---|---|---|---|
| Before VDMean ± SD | After VDMean ± SD | ||
| Frequency domain parameters | |||
| VLF (Log10 s) | 2.2 ± 0.4 | 2.4 ± 0.5 | <0.05 |
| LF (Log10 s) | 1.9 ± 0.5 | 2.5 ± 0.9 | <0.001 |
| HF (Log10 s) | 1.7 ± 0.5 | 2.2 ± 0.8 | 0.01 |
| TP (Log10 s) | 2.5 ± 0.4 | 2.8 ± 0.6 | <0.05 |
| Time domain parameters | |||
| RRmin (s) | 0.66 ± 0,094 | 0.62 ± 0.16 | 0.715 |
| RRmax (s) | 0.77 ± 0.11 | 0.94 ± 0.51 | <0.05 |
| RRNN (s) | 0.71 ± 0.10 | 0.76 ± 0.09 | <0.05 |
| SDNN (s) | 0.02 ± 0.01 | 0.03 ± 0.02 | <0.01 |
| Cardiac autonomic reactivity tests | |||
| Respiratory coefficient | 1.2 ± 0.3 | 1.2 ± 0.2 | 0.395 |
| Valsalva coefficient | 1.4 ± 0.4 | 1.5 ± 0.6 | 0.897 |
| 30/15 ratio | 1.2 ± 0.3 | 1.2 ± 0.2 | 0.357 |
| SBP reduction (orthostase) | 6.9 ± 14.1 | 9.2 ± 14.6 | 0.639 |
CAN, Cardiovascular autonomic neuropathy; VLF, Very low frequency; LF, Low frequency; HF, High frequency; TP, Total power; SBP, Systolic blood pressure; RRmin, smallest RR interval; RRmax, Biggest RR interval; RRNN, mean RR regular intervals; SDNN, Standard deviation of RR regular intervals; NS, Not significant.