Table 1.
Characteristics of the NAFLD and non-NAFLD groups in individuals with normal uric acid.
| Non-NAFLD | NAFLD | P | |
|---|---|---|---|
| n | 196 | 86 | |
| Gender | 0.224 | ||
| Female, n (%) | 122(62.2) | 60(69.8) | |
| Male, n (%) | 74(37.8) | 26(30.2) | |
| Age, years | 53.8 ± 11.2 | 53.5 ± 8.8 | 0.799 |
| BMI, kg/m2 | 24.65 ± 2.92 | 28.42 ± 3.83 | <0.001 |
| WC, cm | 84.89 ± 8.61 | 92.27 ± 9.60 | <0.001 |
| SBP, mmHg | 128.15 ± 19.89 | 129.83 ± 17.75 | 0.503 |
| DBP, mmHg | 74.61 ± 9.78 | 76.59 ± 9.96 | 0.121 |
| TC, mmol/L | 5.43 ± 1.07 | 5.71 ± 1.09 | 0.045 |
| LnTG, mmol/L | 0.22 ± 0.52 | 0.61 ± 0.54 | <0.001 |
| HDL-C, mmol/L | 1.34 ± 0.39 | 1.21 ± 0.22 | 0.002 |
| LDL-C, mmol/L | 2.77 ± 0.74 | 3.08 ± 0.71 | 0.001 |
| SUA/Cr | 3.90 ± 0.89 | 4.56 ± 1.51 | <0.001 |
| FBG, mmol/L | 5.95(5.38-6.66) | 6.09(5.54-7.24) | 0.054 |
| 2h PG, mmol/L | 7.23(5.89-8.45) | 8.15(6.33-11.72) | 0.003 |
| AUCGlu | 1050.38(865.58-1284.38) | 1161.45(962.25-1595.96) | 0.006 |
| FCP, ng/ml | 1.15(0.86-1.40) | 1.65(1.28-2.20) | <0.001 |
| 2hCP, ng/ml | 4.80(3.52-6.32) | 6.71(4.34-8.55) | <0.001 |
| AUCCP | 541.35(440.06-690.79) | 659.25(510.56-868.39) | <0.001 |
| HbA1c, % | 5.5(5.2-5.8) | 5.7(5.45-6.30) | 0.001 |
| LnHOMA-IR | 0.81 ± 0.64 | 1.28 ± 0.58 | <0.001 |
| ALT, U/L | 21.1(16.5-27.9) | 28.1(20.9-42.6) | <0.001 |
| AST, U/L | 21.8(18.6-25.1) | 23.0(20.2-28.6) | 0.021 |
| Glucose tolerance status | 0.013 | ||
| Diabetes, n (%) | 41(20.9) | 30(34.9) | |
| Prediabetes, n (%) | 63(32.1) | 30(34.9) | |
| NGT, n (%) | 92(46.9) | 26(30.2) | |
Data were presented as mean ± standard deviation, number (percentage), or median (25th–75th percentile). NAFLD, non-alcoholic fatty liver disease; BMI, body mass index; WC, waist circumference; SBP, systolic blood pressure; DBP, diastolic blood pressure; TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; SUA/Cr, serum uric acid to creatinine ratio; FBG, fasting blood glucose; 2h PG, 2-h post-load glucose; AUCGlu, area under the curve of glucose; FCP, fasting C-peptide; 2hCP, 2-h post-load C-peptide; AUCCP, area under the curve of C-peptide; HbA1c, hemoglobin A1c; HOMA-IR, homeostatic model assessment of insulin resistance; ALT, alanine aminotransferase; AST, aspartate aminotransferase; NGT, normal glucose tolerance.