Table 1.
Clinical characteristics of 68 patients with HCC according to circRASGRF2 expression level
| Variable | circRASGRF2 |
||
|---|---|---|---|
| Low | High | p Value | |
| All cases | 34 | 34 | |
| Age, years, ≥50:<50 | 16:18 | 18:16 | 0.808 |
| Sex, male:female | 19:15 | 22:12 | 0.620 |
| HBsAg, positive:negative | 16:18 | 19:15 | 0.628 |
| Liver cirrhosis, with:without | 12:22 | 15:19 | 0.621 |
| AFP, μg/L, >20:≤20 | 14:20 | 16:18 | 0.807 |
| Pathological satellite, present:absent | 17:17 | 19:15 | 0.808 |
| No. tumors, multiple:solitary | 6:28 | 8:26 | 0.765 |
| Edmondson’s grade, III+IV:I+II | 11:23 | 22:12 | 0.014∗ |
| Tumor size, cm, >5:≤5 | 11:23 | 24:10 | 0.003∗ |
| Microvascular invasion, present:absent | 4:30 | 12:22 | 0.043∗ |
| Encapsulation, incomplete:complete | 18:16 | 20:14 | 0.808 |
| TNM stage, II+III:I | 10:24 | 20:14 | 0.027∗ |
| BCLC stage, B+C:A | 9:25 | 24:10 | 0.0006∗ |
Α χ2 test was used to test the association between two categorical variables. AFP, alpha-fetoprotein; BCLC, Barcelona Clinic Liver Cancer; HCC, hepatocellular carcinoma; HBsAg, hepatitis B surface antigen; TNM, tumor-node-metastasis. ∗Statistically significant.