Table 1.

Estimated mean and standard deviations for all repolarization parameters.

Current	Param	Distribution*	Co-variates†	Mean	Std dev	${\widehat{\sigma }}_{\text{N}}$ (%)	${\widehat{\sigma }}_{LN}$ (%)
IK1	gK1	Lognormal	Ez, kz	0.772	0.217		28
	Ez	Normal	gK1, kz	−92.1	5.01	5
	kz	Lognormal	gK1, Ez	12.4	1.73		14
Ito	gto	Lognormal	Er, kr	0.172	0.0676		39
	Er	Normal	gto, kr	14.4	5.78	6
	kr	Lognormal	gto, Er	11.8	1.63		14
	Es	Normal	ks	−48.1	6.12	6
	ks	Lognormal	Es	3.29	0.755		23
	${\tau }_s^{*}$	Lognormal		9.91	1.28		13
ICaL	gCaL	Lognormal		0.108	0.0378		35
	Ed	Normal		0.7	3.71	4
	kd	Lognormal		4.3	0.742		17
	Ef	Normal		−15.7	7.01	7
	kf	Lognormal		4.6	0.62		13
	${\tau }_f^{*}$	Lognormal		30.4	9.45		31
IKr	gKr	Lognormal		0.056	0.0224‡		40‡
	Exr	Normal		−26.6	4.43	4
	kxr	Lognormal		6.5	0.949		15
	${\tau }_{xr}^{*}$	Lognormal		334	133.6‡		40‡
	Ey	Normal		−49.6	7.8	8
	ky	Lognormal		23.5	1.5		6
IKs	gKs	Lognormal		0.008	0.0032‡		40‡
	Exs	Normal		24.6	33.94	34
	kxs	Lognormal		12.1	1.70		14
	${\tau }_{xs}^{*}$	Lognormal		628	140		22

See Appendix for actual distributions. Units: g_X in mS/cm², E_X in mV, k_X mV, ${\tau }_X^{*}$ in ms.

^*Type of distributions was prescribed, not inferred.

^†Co-variates based on availability of data, not inferred.

^‡Standard deviation chosen so ${\widehat{\sigma }}_{\text{LN}}=40\%$; see text. ${\widehat{\sigma }}_N$ and ${\widehat{\sigma }}_{\text{LN}}$ are relative measures of uncertainty; see text for precise definitions. INa parameters and EK, ENa, ECa were fixed at nominal values from Pathmanathan et al. (2019).