Figure 2.

Immunolocalization of heavy chains (HCs) in adult mouse tissues: (A) liver, (B) kidney, (C) lung, and (D) growth plate. HCs were detected via immunohistochemistry using a polyclonal antibody raised against human serum inter-α-trypsin inhibitor and reactivity to mouse HCs, and specific staining is shown in brown. Annotations for tissue features include the following: a, artery; b, bronchiolar epithelial cells; co, connective tissue; g, glomerulus; h, hypertrophic zone; o, ossification; p, proliferative zone; t, proximal convoluted tubular cells; v, vessel. Images shown at 100× magnification. Reprinted with permission from Kobayashi et al.²¹