The protein expression of GPC1, GPC2, and GPC3 in cancers. GPC1 protein
level is increased in PDAC tissue compared with normal pancreas as
determined by IHC using the GPC1-specific mouse monoclonal antibody
(MAb) HM2. GPC2 protein is presented in NB tissue but not in normal
peripheral nerve tissue as determined by IHC using the anti-GPC2 mouse
MAb CT3. GPC3 is overexpressed in HCC tissue compared with normal liver
tissue using the GPC3-specific mouse MAb YP7 by IHC. Images were
obtained under 20 × magnification. Scale bar = 200 µm. Abbreviations:
HCC, hepatocellular carcinoma; IHC, immunohistochemistry; NB,
neuroblastoma; PDAC, pancreatic ductal adenocarcinoma.