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. 2020 Jul 6;68(12):841–862. doi: 10.1369/0022155420933709

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© The Author(s) 2020

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Figure 1. — The protein expression of GPC1, GPC2, and GPC3 in cancers. GPC1 protein level is increased in PDAC tissue compared with normal pancreas as determined by IHC using the GPC1-specific mouse monoclonal antibody (MAb) HM2. GPC2 protein is presented in NB tissue but not in normal peripheral nerve tissue as determined by IHC using the anti-GPC2 mouse MAb CT3. GPC3 is overexpressed in HCC tissue compared with normal liver tissue using the GPC3-specific mouse MAb YP7 by IHC. Images were obtained under 20 × magnification. Scale bar = 200 µm. Abbreviations: HCC, hepatocellular carcinoma; IHC, immunohistochemistry; NB, neuroblastoma; PDAC, pancreatic ductal adenocarcinoma.