Table 5.

Proteomic databases for DTD

Database	Description	Application
PRIDE Archive [84]	The PRIDE is a public data repository for proteomics, including protein and peptide identifications, post-translational modifications and supporting spectral evidence. https://www.ebi.ac.uk/pride/archive/	Drug target identification
ProteomicsDB [85]	PDB is a large collection of quantitative MS-based proteomics data across various tissue types as well as protein–protein interaction information, functional annotation, target deconvolution, cell sensitivity and reference MS data. https://www.proteomicsdb.org/	Drug target identification Drug target efficacy/potency
Human Proteome Map [88]	Hosts high-resolution MS proteomic data representing 17 adult tissues, 6 primary hematopoietic cells and 7 fetal tissues resulting in >84% human proteome coverage. http://www.humanproteomemap.org/	Drug target identification Biomarkers
Human proteome atlas [89]	Collects expression and localization of majority of human protein-coding genes based on both RNA and protein data. The HPA also employs antibody-based proteomics and transcriptomics profiling methods to locate and identify proteins in tissues and cell types. http://www.proteinatlas.org/	Druggable proteome Drug target efficacy and specificity