Table 4.

Comparison of histological and immunohistochemical characteristics between HER2-positive BCP diagnosed during first trimester versus HER2 BCP diagnosed during second and third trimester.

	HER2-positive BCP First Trimester (n = 14)	HER2 BCP Second and third Trimester (n = 34)	P
Tumor size (mean) (mm)	38.2	42.3	0.35
Tumor size (TNM classification)
T1	4 (28)	6 (18)	0.79
T2	4 (28)	14 (41)
T3	3 (21)	7 (21)
T4	2 (14)	6 (18)
T4B	2 (14)	0 (0)
T4D	0 (0)	6 (18)	0.16
Missing data	1 (7)	1 (3)
N+, n(%)	8 (57)	24 (71)	0.50
M+, n(%)	0 (0)	8 (24)	0.08
Tumor type, n(%)			0.29
Invasive ductal carcinoma	13 (93)	34 (100)
Invasive lobular carcinoma	1 (7)	0 (0)
Focality, n(%)			0.14
Unifocal tumor	13 (93)	24 (71)
Multifocal tumor	1 (7)	10 (29)
Grade SBR, n(%)			0.33
1	1 (7)	0 (0)
2	3 (21)	11 (32)
3	10 (71)	23 (68)
HR status, n(%)			0.32
Negative	3 (21)	14 (41)
Positive	11 (78)	20 (59)
Ki67 rate, n(%)
<15%	0 (0)	0 (0)	0.08
≥15%	12 (86)	34 (100)
NC	2 (14)	0 (0)
<20%	1 (7)	2 (6)	0.10
≥20%	11(79)	32 (94)
NC	2 (14)	0 (0)